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pentobarbital will lessen the extent or effect of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers could reduce partiaprevir and ritonavir stages, and so decreased efficacy of Viekira Pakbuprenorphine subdermal implant and pentobarbital both equally